Organ meat consumption and risk of nonalcoholic fatty liver disease: the TCLSIH study

Autor: Huiping, Li, Xiaoxi, Zheng, Sabina, Rayamajhi, Amrish, Thapa, Ge, Meng, Qing, Zhang, Li, Liu, Hongmei, Wu, Yeqing, Gu, Shunming, Zhang, Tingjing, Zhang, Xuena, Wang, Jun, Dong, Zhixia, Cao, Xu, Zhang, Xinrong, Dong, Shaomei, Sun, Xing, Wang, Ming, Zhou, Qiyu, Jia, Kun, Song, Kaijun, Niu
Rok vydání: 2022
Zdroj: The British journal of nutrition.
ISSN: 1475-2662
Popis: Prospective cohort studies linking organ meat consumption and nonalcoholic fatty liver disease (NAFLD) are limited, especially in Asian populations. This study aimed to prospectively investigate the association between organ meat consumption and risk of NAFLD in a general Chinese adult population. This prospective cohort study included a total of 15,568 adults who were free of liver disease, cardiovascular disease, and cancer at baseline. Dietary information was collected at baseline using a validated food frequency questionnaire. NAFLD was diagnosed by abdominal ultrasound after excluding other causes related to chronic liver disease. Cox proportional regression models were used to assess the association between organ meat consumption and risk of NAFLD. During a median of 4.2 years of follow-up, we identified 3,604 incident NAFLD cases. After adjusting for demographic characteristics, lifestyle factors, vegetable, fruit, soft drink, seafood, and red meat consumption, the multivariable hazard ratios (95% confidence intervals) for incident NAFLD across consumption of organ meat were 1.00 (reference) for almost never, 1.04 (0.94, 1.15) for tertile 1, 1.08 (0.99, 1.19) for tertile 2, and 1.11 (1.01, 1.22) for tertile 3, respectively (P for trend0.05). Such association did not differ substantially in the sensitivity analysis. Our study indicates that organ meat consumption was related to a modestly higher risk of NAFLD among Chinese adults. Further investigations are needed to confirm this finding.
Databáze: OpenAIRE