Biallelic Variants in

Autor: Alessia, Nasca, Andrea, Legati, Megi, Meneri, Melisa Emel, Ermert, Chiara, Frascarelli, Nadia, Zanetti, Manuela, Garbellini, Giacomo Pietro, Comi, Alessia, Catania, Costanza, Lamperti, Dario, Ronchi, Daniele, Ghezzi
Rok vydání: 2022
Předmět:
Zdroj: Cells. 11(6)
ISSN: 2073-4409
Popis: Endonuclease G (ENDOG) is a nuclear-encoded mitochondrial-localized nuclease. Although its precise biological function remains unclear, its proximity to mitochondrial DNA (mtDNA) makes it an excellent candidate to participate in mtDNA replication, metabolism and maintenance. Indeed, several roles for ENDOG have been hypothesized, including maturation of RNA primers during mtDNA replication, splicing of polycistronic transcripts and mtDNA repair. To date
Databáze: OpenAIRE