[Role of individual genes in the manifestation of the pathogenicity of influenza viruses]

Autor: V V, Skovorodka, V R, Farashian, R Ia, Podcherniaeva, V M, Zhdanov
Rok vydání: 1983
Předmět:
Zdroj: Voprosy virusologii. 28(6)
ISSN: 0507-4088
Popis: The study elucidated the role of individual genes in manifestation of mouse pathogenicity by A/PR/8/34 and A/Seal/Massachusetts/1/80. The viruses were studied by the methods of recombination and molecular hybridization. The gene analysis showed that in a permissive system the pathogenicity of A/PR/8/34 strain was not associated with HA and NA surface glycoproteins. Gene P1 plays the decisive role in manifestation of pathogenicity of this strains.
Databáze: OpenAIRE