Autor: |
P F, Fransz, S, Armstrong, J H, de Jong, L D, Parnell, C, van Drunen, C, Dean, P, Zabel, T, Bisseling, G H, Jones |
Rok vydání: |
2000 |
Předmět: |
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Zdroj: |
Cell. 100(3) |
ISSN: |
0092-8674 |
Popis: |
We have constructed an integrated cytogenetic map of chromosome arm 4S of Arabidopsis thaliana. The map shows the detailed positions of various multicopy and unique sequences relative to euchromatin and heterochromatin segments. A quantitative analysis of the map positions at subsequent meiotic stages revealed a striking pattern of spatial and temporal variation in chromatin condensation for euchromatin and heterochromatin. For example, the centromere region consists of three domains with distinguishable structural, molecular, and functional properties. We also characterized a conspicuous heterochromatic knob of approximately 700 kb that accommodates a tandem repeat and several dispersed pericentromere-specific repeats. Moreover, our data provide evidence for an inversion event that relocated pericentromeric sequences to an interstitial position, resulting in the heterochromatic knob. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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