Does preoperative biliary drainage compromise the long-term survival of patients with pancreatic head carcinoma?

Autor: Yoshiaki, Murakami, Kenichiro, Uemura, Yasushi, Hashimoto, Naru, Kondo, Naoya, Nakagawa, Hayato, Sasaki, Naoto, Hatano, Toshiaki, Kohmo, Taijiro, Sueda
Rok vydání: 2014
Předmět:
Zdroj: Journal of surgical oncology. 111(3)
ISSN: 1096-9098
Popis: The aim of this study was to determine the impact of preoperative biliary drainage (PBD) on long-term survival in patients with pancreatic head carcinoma after surgical resection.Medical records of 160 patients with pancreatic head carcinoma who underwent surgical resection were reviewed retrospectively. Clinicopathological parameters including long-term survival were compared between patients who did and did not undergo PBD.Overall survival of patients who underwent PBD (n = 93) was significantly worse than that of patients who did not (n = 67) by univariate analysis (P = 0.030). However, multivariate analysis revealed that PBD was not an independent prognostic factor for overall survival (P = 0.227). Patients who underwent percutaneous transhepatic biliary drainage (PTBD) had significantly worse survival than patients who underwent endoscopic retrograde biliary drainage (ERBD, P = 0.038) and patients who did not undergo PBD (P = 0.001). The rate of peritoneal recurrence in patients who underwent PTBD was significantly higher than that of patients who underwent ERBD (P = 0.033) or patients who did not undergo PBD (P = 0.034).PBD may not affect the long-term survival of patients with pancreatic head carcinoma if ERBD is used.
Databáze: OpenAIRE