[Prevention of functional impairments of cardiac muscle mitochondria in emotional-painful stress]

Autor:	F Z, Meerson, V I, Lifant'ev, V V, Malyshev
Rok vydání:	1984
Předmět:	Male Hydroxybutyrates Pain Calcium Channel Blockers Propranolol Ion Channels Mitochondria Heart Oxidative Phosphorylation Rats Sarcolemma Verapamil Animals Humans Calcium Sodium Oxybate Stress Psychological
Zdroj:	Voprosy meditsinskoi khimii. 30(1)
ISSN:	0042-8809
Popis:	In experiments with 216 male rats emotional-painful stress impaired distinctly the oxidative phosphorylation and Ca2+ transport in heart muscle mitochondria. When gamma-hydroxybutyric acid, inderal, antioxidants ionol and isoptin were used as selective inhibitors of definite steps in the pathogenetic chain of stress heart impairments, these impairments of the mitochondrial functions were effectively prevented at the step of regulatory mechanisms responsible for the stress reactions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::788413ccf48e33f3c92bacb1b1c66def https://pubmed.ncbi.nlm.nih.gov/6324483 Zobrazit plný text záznamu