What constitutes an adequate antidepressant trial for fluoxetine?

Autor:	E, Schweizer, K, Rickels, J D, Amsterdam, I, Fox, G, Puzzuoli, C, Weise
Rok vydání:	1990
Předmět:	Adult Male Psychiatric Status Rating Scales Clinical Trials as Topic Depressive Disorder Outcome and Process Assessment Health Care Dose-Response Relationship Drug Fluoxetine Body Weight Humans Female Drug Administration Schedule
Zdroj:	The Journal of clinical psychiatry. 51(1)
ISSN:	0160-6689
Popis:	One hundred and eight patients with major depression were treated with fluoxetine 20 mg/day for 3 weeks. Patients who failed to respond to this open-label treatment were randomly assigned either to receive fluoxetine 60 mg/day for 5 weeks or to continue treatment with fluoxetine 20 mg/day for an additional 5 weeks. Both treatment groups demonstrated a statistically significant reduction in depressive symptoms, indicating that continued treatment with low-dose fluoxetine may be as effective as an increase in dose in achieving a favorable clinical outcome.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::7630e81d027bab9ecfef4975a489dc06 https://pubmed.ncbi.nlm.nih.gov/2403998 Zobrazit plný text záznamu