| Autor: |
Qian-kun, Zhu, Gui-zhen, He, Hai-long, Li |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 37(4) |
| ISSN: |
1000-503X |
| Popis: |
To investigate the effect of intestinal ischemia-reperfusion on the protein expression of chemerin in C57BL/6J mice.A total of 16 mice (C57BL/6J, specific pathogen free level) were randomly assigned into two groups (n=8 each): the intestinal ischemia-reperfusion group and the sham group. The intestinal ischemia-reperfusion state was achieved by blocking the super-mesenteric artery. After 60 minutes of ischemia followed by 60 minutes of reperfusion,we determined the protein level of chemerin in various organs and tissues by enzyme-linked immunosorbent assay and Western blot. The sham group underwent the same operation process except for the blocking of the super-mesenteric artery.The protein level of chemerin was significantly elevated in distinctive organs and tissues in the state of intestinal ischemia-reperfusion (P0.05).The intestinal ischemia-reperfusion can remarkably increase the protein expression of chemerin in some organs and tissues. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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