[Multi-systemic toxicity of colchicine and renal failure: apropos of a case]

Autor: L, Rosset, E, Descombes, G, Fellay, C, Regamey
Jazyk: francouzština
Rok vydání: 1999
Předmět:
Zdroj: Schweizerische medizinische Wochenschrift. 128(49)
ISSN: 0036-7672
Popis: The use of colchicine can produce various side effects, but multiorgan toxicity is rare. We report the first Swiss case of multiorgan toxicity involving typical neuromuscular lesions. Muscular biopsy is a valuable tool in confirming the diagnosis. Renal insufficiency and hepatobiliary diseases are predisposing factors for such complications. Colchicine pharmacology in the case of renal insufficiency is discussed.
Databáze: OpenAIRE