Severe intravascular hemolysis due to autoantibodies stimulated by blood transfusion

Autor: D, Chan, G D, Poole, M, Binney, M D, Hamon, J A, Copplestone, A G, Prentice
Rok vydání: 1996
Zdroj: Immunohematology. 12(2)
ISSN: 0894-203X
Popis: Autoantibodies may cause severe hemolytic anemia, but only rarely are they the cause of a hemolytic transfusion reaction due to the destruction of transfused allogeneic blood. In two patients, autoantibody was detected shortly after blood transfusion. The first case was a D-negative patient who produced an autoanti-Ce and subsequently developed hemoglobinuria and hyperbilirubinemia. The second case was a patient who developed an autoanti-Wrb that caused severe hemolysis that resulted in death.
Databáze: OpenAIRE