[Effect of various types of antihypertensive therapy on elasticity of arterial wall in elderly patients with hypertensive disease and nonvalvular atrial fibrillation]

Autor:	V I, Shevelev, S G, Kanorskiĭ
Rok vydání:	2012
Předmět:	Aged 80 and over Male Age Factors Elasticity Carotid Arteries Treatment Outcome Vascular Stiffness Atrial Fibrillation Hypertension Elasticity Imaging Techniques Humans Female Antihypertensive Agents Aged Follow-Up Studies
Zdroj:	Kardiologiia. 52(8)
ISSN:	0022-9040
Popis:	Basing on the data of ultrasound study we compared effects of various antihypertensive therapies on elastic properties of common carotid arteries and the thoracic aorta in 133 patients aged 65-80 years with nonvalvular atrial fibrillation (AF). The use of perindopril, lercanidipin, valsartan and its combination with rosuvastatin was associated with elevation of the distensibility index of common carotid artery and lowering of coefficient of stiffness of aortic wall compared with the initial state. Combination of valsartan (80-160 mg/day) with rosuvastatin 10 (mg/day) produced most pronounced effect on compliance of vascular wall compared with other variants of treatment. Combination of valsartan and rosuvastatin can be considered an optimal strategy of antihypertensive therapy allowing to improve elastic properties of arterial wall in elderly patients with nonvalvular AF.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::6eaa707caa34c30354e71d4e4d7030ce https://pubmed.ncbi.nlm.nih.gov/23098396 Zobrazit plný text záznamu