Incidence and predictors of left atrial appendage thrombus on transesophageal echocardiography before elective cardioversion

Autor: Felix K, Wegner, Robert, Radke, Christian, Ellermann, Julian, Wolfes, Alicia J, Fischer, Helmut, Baumgartner, Lars, Eckardt, Gerhard-Paul, Diller, Stefan, Orwat
Rok vydání: 2021
Předmět:
Zdroj: Scientific reports. 12(1)
ISSN: 2045-2322
Popis: Guidelines recommend transesophageal echocardiography (TEE) before cardioversion in thrombogenic arrhythmias when the requirement of ≥ 3 weeks of anticoagulation is not met. Current data to support this approach, especially with direct oral anticoagulants (DOAC), are scarce. We analyzed consecutive elective pre-cardioversion TEE in a high-volume electrophysiology center for the occurrence of left atrial appendage (LAA) thrombi or reduced LAA flow velocity. Possible predictors were recorded and compared in a multivariate logistic regression analysis. Consecutive pre-cardioversion TEE in 512 patients (148 female, median age 69 years) were included. In all patients, indication for TEE was either intake of anticoagulation 3 weeks before cardioversion or uncertain adherence to the prescribed anticoagulation regimen. Of the 512 TEE, 19 (3.7%) depicted a LAA thrombus. An additional 41 patients (8.0%) showed either a reduced LAA flow velocity (≤ 20 cm/s), LAA sludge, or both. In a multivariate logistic regression analysis, QRS width on admission 12-lead ECG emerged as a possible predictor of LAA thrombus and reduced LAA flow (p = 0.008). Noteworthy, a high CHA
Databáze: OpenAIRE