[A comparative study of the sensitivity and specific activity of an immunoenzyme test system for determining class-M antibodies to the hepatitis A virus]

Autor: T V, Kalashnikova, L G, Karpovich, N M, Nikitiuk, M A, Gorbunov, E E, Evreinova, I V, Nel'ga, Iu Iu, Kusov, M S, Balaian
Rok vydání: 1991
Předmět:
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii. (5)
ISSN: 0372-9311
Popis: The diagnostic value of the first experimental production batches of assay kit "DIAGN-A-HEP", produced at the Institute of Poliomyelitis and Viral Encephalitides (USSR Acad. Med. Sci.) and intended for the determination of IgM to hepatitis A virus (HAV) in the enzyme immunoassay (EIA), has been studied in comparison with that of the internationally known and widely approved commercial EIA system "HAVAB-MEIA" for the determination of antibodies to HAV (the product of Abbott, USA). The study has revealed that the EIA kit "DIAGN-A-HEP" is highly sensitive and specific, and the diagnostic value of this kit is not inferior to that of the commercial assay system "HAVAB-MEIA". On the basis of this study the use of the EIA kits "DIAGN-A-HEP" in medical practice has been allowed by the decree of the Ministry of Health of the USSR.
Databáze: OpenAIRE