Effect of a mixture of GOS/FOS
Autor: | Gabriel, Bryk, Magalí Zeni, Coronel, Carlos, Lugones, Patricia, Mandalunis, María Esther, Rio, Ariel Felix, Gualtieri, María Luz Pita Martín, de Portela, Susana Noemí, Zeni |
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Rok vydání: | 2015 |
Předmět: |
Male
Bone Development Body Weight Tryptophanase Biological Availability Oligosaccharides Protein-Energy Malnutrition Urease Diet Rats Calcium Dietary Feces Calcification Physiologic Prebiotics Intestinal Absorption Bone Density Animals Phosphorus Dietary Magnesium Femur Growth Plate Rats Wistar Cecum Trisaccharides Glucuronidase |
Zdroj: | European journal of nutrition. 55(8) |
ISSN: | 1436-6215 |
Popis: | During growth, protein deprivation impairs epiphyseal growth plate (EGP) height, bone volume (BV) and endochondral ossification. During catch-up growth, Ca availability becomes essential to ensure the extra amount needed to achieve optimal peak bone mass and strength. GOS and FOS improve mineral absorption in the colon.The effect of a mixture of GOS/FOSTo induce protein malnutrition, rats were fed a low protein diet: 4 % (LPD) during 1 week and then were randomly assigned to recovery groups (R) until day 50 (T = 50) as follows: R0.5 %: NCa; RP0.5 %: NCa + 5.3 % GOS/FOSBody weight and length increased in C groups throughout the study; both were arrested in all R during LPD consumption and increased immediately after re-feeding. Independently of dietary Ca content, LS counts, β-glucosidase and Ca, P and Mg absorption increased, whereas cecum pH, β-glucuronidase, urease and tryptophanase decreased in RP0.5 %: and RP0.3 %: as compared to the other studied groups (p 0.01). Prebiotic consumption decreased CTX levels and increased femur Ca, Mg and P contents, total skeleton bone mineral content, proximal tibia and spine BMD, BV, EGP height and hypertrophic zone thickness, stiffness and elastic modulus as compared to recovery groups fed the prebiotic-free diets.Under the present experimental conditions, GOS/FOS |
Databáze: | OpenAIRE |
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