[Enterobacteria producers of extended-spectrum beta-lactamase in a hospital from Venezuela]
| Autor: | Rosa María, Tedesco Maiullari, Armando, Guevara |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
Male Adolescent beta-Lactam Resistance beta-Lactamases Substrate Specificity Young Adult Age Distribution Bacterial Proteins Enterobacteriaceae Escherichia coli Humans Viremia Sex Distribution Child Escherichia coli Infections Aged Aged 80 and over Enterobacteriaceae Infections Infant Middle Aged Venezuela Klebsiella Infections Klebsiella pneumoniae Cross-Sectional Studies Child Preschool Urinary Tract Infections Female |
| Zdroj: | Le infezioni in medicina. 20(2) |
| ISSN: | 2532-8689 |
| Popis: | The emergence of antimicrobial resistance due to extended-spectrum beta-lactamase (ESBL) has significant clinical impact and is a public health problem. The aim of the present study was to determine the frequency of infections by ESBL-producing enterobacteria in patients hospitalized in the "Ruiz y Paez" Hospital (CHRP) from Cuidad Bolivar, Venezuela, from January to July 2011. We determined the ESBL production from all isolates of E. coli, K. pneumoniae, K. oxytoca and P. mirabilis, using a double disk synergy test and combined disk method. Of the Enterobacteriaceae isolated, 20.3% (53) were ESBL producers, the main ones being K. pneumoniae and E. coli with 56.6% and 43.3% respectively: 15.7% of all E. coli and 47.6% of all K. pneumoniae were ESBL producers, and were more frequent in the purulent samples (43.3%) and blood (30.1%). The service with the greatest number of isolated ESBL-producing enterobacteria was medicine (26.4%) followed by perinatology (24.5%). We concluded that the CHRP has a high rate of ESBL-producing enterobacteria, mainly K. pneumoniae. |
| Databáze: | OpenAIRE |
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