Central vein catheter-related thrombosis in intensive care patients: incidence, risks factors, and relationship with catheter-related sepsis
| Autor: | J F, Timsit, J C, Farkas, J M, Boyer, J B, Martin, B, Misset, B, Renaud, J, Carlet |
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| Rok vydání: | 1998 |
| Předmět: |
Male
Catheterization Central Venous Time Factors Critical Care Enterobacter Subclavian Vein Serratia Infections Risk Factors Sepsis Confidence Intervals Humans Pseudomonas Infections Prospective Studies APACHE Aged Ultrasonography Doppler Duplex Heparin Incidence Age Factors Enterobacteriaceae Infections Anticoagulants Thrombosis Middle Aged Staphylococcal Infections Klebsiella Infections Female Jugular Veins Acinetobacter Infections |
| Zdroj: | Chest. 114(1) |
| ISSN: | 0012-3692 |
| Popis: | To evaluate the incidence and risk factors for catheter-related central vein thrombosis in ICU patients.Observational prospective multicenter study.An 8-bed surgical ICU, a 10-bed surgical cardiovascular ICU, and a 10-bed medical-surgical ICU.During an 18-month period, 265 internaljugular or subclavian catheters were included. Veins were explored by duplex scanning performed just before or24 h after catheter removal. Suspected risk factors of catheter-related central vein thrombosis were recorded.None.Fifty-seven catheters were excluded from the analysis. Therefore 208 catheters were analyzed. Mean age of patients was 64+/-15 years, simplified acute physiologic score was 12+/-5, organ system failure score at insertion was 1+/-1, and mean duration of catheterization was 9+/-5 days. A catheter-related internal jugular or subclavian vein thrombosis occurred in 33% of the cases (42% [95% confidence interval (CI), 34 to 49%] and 10% [95% CI, 3 to 18%], respectively). Thrombosis was limited in 8%, large in 22%, and occlusive in 3% of the cases. Internal jugular route (relative risk [RR], 4.13; 95% CI, 1.72 to 9.95), therapeutic heparinization (RR 0.47; 95% CI, 0.23 to 0.99), and age64 years (RR, 2.44; 95% CI, 2.05 to 3.19) were independently associated with catheter-related thrombosis. Moreover, the risk of catheter-related sepsis was 2.62-fold higher when thrombosis occurred (p=0.011).Catheter-related central vein thrombosis is a frequent complication of central venous catheterization in ICU patients and is closely associated with catheter-related sepsis. |
| Databáze: | OpenAIRE |
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