Genetic transformation in Streptococcus mutans requires a peptide secretion-like apparatus

Autor:	F C, Petersen, A A, Scheie
Rok vydání:	2001
Předmět:	DNA Bacterial Phosphoproteins DNA-Binding Proteins Streptococcus mutans Bacterial Proteins Bacteriocins Genes Bacterial Mutation DNA Transposable Elements Humans ATP-Binding Cassette Transporters Gene Silencing Transformation Bacterial Genome Bacterial
Zdroj:	Oral microbiology and immunology. 15(5)
ISSN:	0902-0055
Popis:	Competence for genetic transformation in Streptococcus pneumoniae and Streptococcus gordonii involves the ComAB secretion apparatus, which is thought to export the competence-stimulating peptide. Homologous secretory systems are also used for the export of certain bacteriocins and bacteriocin-like peptides. In this study, a similar secretory apparatus was found in the Streptococcus mutans genome, and its role in transformation was investigated. Gene inactivation resulted in a mutant deficient in transformability. We suggest that secretion of a peptide, possibly the competence-stimulating peptide itself, is involved in competence induction also in S. mutans.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::5f7cdcb57583a603b3bb318cc2d070a2 https://pubmed.ncbi.nlm.nih.gov/11154426 Zobrazit plný text záznamu Plný text