[Spatial structure of a Fab-fragment of a monoclonal antibody to human interleukin-2 in two crystalline forms at a resolution of 2.2 and 2.9 angstroms]

Autor:	A V, Fokin, P V, Afonin, I Iu, Mikhaĭlova, I N, Tsygannik, T Iu, Mareeva, V A, Nesmeianov, W, Pangborn, N, Lee, W, Duax, E, Siszak, V Z, Pletnev
Rok vydání:	2000
Předmět:	Immunoglobulin Fab Fragments Protein Conformation Molecular Sequence Data Antibodies Monoclonal Humans Interleukin-2 Stereoisomerism Amino Acid Sequence Binding Sites Antibody Antigens Crystallography X-Ray
Zdroj:	Bioorganicheskaia khimiia. 26(8)
ISSN:	0132-3423
Popis:	The three-dimensional structure of the antigen-binding fragment of a monoclonal antibody to human interleukin-2 was determined in two crystal forms by the X-ray method of molecular replacement at 2.2 and 2.9 A resolutions. The spatial structure of the protein and the stereochemistry of its antigen-binding site were analyzed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::5f373ebafd433440e52e5f96b51d1096 https://pubmed.ncbi.nlm.nih.gov/11040993 Zobrazit plný text záznamu