Increased Uptake of Technetium-99m-Hexamethylpropyleneamine Oxime Related to Primary Leptomeningeal Melanoma

Autor: Sagiuchi, Takao, Ishii, Katsumi, Utsuki, Satoshi, Asano, Yuuji, Tsukahara, Shinya, Kan, Shinichi, Fujii, Kiyotaka, Hayakawa, Kazushige
Jazyk: angličtina
Rok vydání: 2002
Předmět:
Zdroj: AJNR Am J Neuroradiol
Popis: Summary: We present an autopsy case of primary leptomeningeal melanoma visualized with technetium-99m-hexamethylpropyleneamine oxime (Tc-99m-HMPAO) single photon emission CT (SPECT) of the brain. Increased uptake of Tc-99m-HMPAO coincided with leptomeningeal enhancement on MR images and with the tumor location of the autopsy findings. It was thought that Tc-99m-HMPAO could correlate closely with melanoma. Tc-99m-HMPAO SPECT clearly showed primary leptomeningeal melanoma and severe hypoperfusion induced by intracranial hypertension and tumor proliferation.
Databáze: OpenAIRE