A parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type

Autor: Hongyuan, Wang, Yuan, Zhao, Marina, Ezcurra, Alexandre, Benedetto, Ann F, Gilliat, Josephine, Hellberg, Ziyu, Ren, Evgeniy R, Galimov, Trin, Athigapanich, Johannes, Girstmair, Maximilian J, Telford, Colin T, Dolphin, Zhizhou, Zhang, David, Gems
Rok vydání: 2017
Zdroj: NPJ aging and mechanisms of disease. 4
ISSN: 2056-3973
Popis: A long-standing belief is that aging (senescence) is the result of stochastic damage accumulation. Alternatively, senescent pathology may also result from late-life, wild-type gene action (i.e., antagonistic pleiotropy, as argued by Williams) leading to non-adaptive run-on of developmental programs (or
Databáze: OpenAIRE