| Autor: |
Christelle, Darnaud, Alexandre, Courtet, Audrey, Schmitt, Pierre, Boutouyrie, Philippe, Bouchard, Maria Clotilde, Carra |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Clinical oral investigations. 25(2) |
| ISSN: |
1436-3771 |
| Popis: |
Severe periodontitis has been associated with endothelial dysfunction and arterial stiffness. The present study aimed to provide a critical appraisal and a meta-analysis of the literature investigating pulse wave velocity (PWV) in patients with and without severe periodontitis and to assess whether treatments influence PWV.English literature was searched on multiple databases up to April 2020 by two independent reviewers. Studies comparing PWV between patients with and without severe periodontitis or assessing the impact of periodontal treatments on PWV were searched and retrieved. Pool data analyses with random effect models were performed. The risk of bias was assessed using Newcastle-Ottawa Scale and RoB2 tools.Seventeen studies were selected. Of these, 10 were used for the meta-analysis. Twelve were cross-sectional studies and 5 interventional studies, including 3176 patients, of whom 1894 had severe periodontitis and 1282 were considered as the controls (without severe periodontitis). Based on carotid-femoral PWV measurement, patients with severe periodontitis (n = 309) have a significantly higher PVW than patients with non-severe periodontitis (n = 213), with a mean difference of 0.84 m/s (95% CI 0.50-1.18; p 0.0001; IThe present study demonstrates that patients with severe periodontitis have higher PWV compared to patients with non-severe periodontitis.Severe periodontitis is associated with arterial stiffness, supporting the mutual involvement of dentists and physicians. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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