Autor: |
Tamas, Alexy, Rajat, Kalra, Marinos, Kosmopoulos, Jason A, Bartos, Andrea, Elliott, Alejandra Gutierrez, Bernal, Cindy M, Martin, Ranjit, John, Andrew W, Shaffer, Ganesh, Raveendran, Adamantios, Tsangaris, Demetris, Yannopoulos |
Rok vydání: |
2022 |
Zdroj: |
European heart journal. Acute cardiovascular care. |
ISSN: |
2048-8734 |
Popis: |
The long-term outcomes of patients treated with extracorporeal cardiopulmonary resuscitation (ECPR) for refractory ventricular tachycardia/ventricular fibrillation (VT/VF) out-of-hospital cardiac arrest (OHCA) remain poorly defined. The purpose of this study was to describe the hospital length of stay and long-term survival of patients who were successfully rescued with ECPR after refractory VT/VF OHCA.In this retrospective cohort study, the length of index admission and long-term survival of patients treated with ECPR after OHCA at a single center were evaluated. In a sensitivity analysis, survival of patients managed with left ventricular assist device (LVAD) implantation or heart transplantation during the same period was also evaluated.Between 1/1/2016 and 12/1/2020, 193 patients were transferred for ECPR considerations and 160 underwent peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO) cannulation. Of these, 54 (33.7%) survived the index admission. These survivors required a median 16 days of intensive care and 24 days total hospital stay. The median follow-up time of the survivors was 1,216 [683, 1461] days. 79.6% and 72.2% were alive at one and four years, respectively. Most deaths within the first year occurred among the patients requiring discharge to a long-term acute care facility. Overall survival rates at four years were similar in the ECPR and LVAD cohorts (p = 0.30) but were significantly higher for transplant recipients (p 0.001).This data suggest that the lengthy index hospitalization required to manage OHCA patients with ECPR is rewarded by excellent long-term clinical outcomes in an expert ECPR program. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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