Autor:	Katharina, Kulikov, Senada, Nozinovic, Stephanie, Kath-Schorr
Rok vydání:	2017
Předmět:	G-Quadruplexes Porphyrins Molecular Structure RNA Stability Humans RNA RNA-Binding Proteins RNA Catalytic Chemistry Techniques Analytical
Zdroj:	Chembiochem : a European journal of chemical biology. 18(11)
ISSN:	1439-7633
Popis:	An unusually thermostable G-quadruplex is formed by a sequence fragment of a naturally occurring ribozyme, the human CPEB3 ribozyme. Strong evidence is provided for the formation of a uniquely stable intermolecular G-quadruplex structure consisting of five tetrad layers, by using CD spectroscopy, UV melting curves, 2D NMR spectroscopy, and gel shift analysis. The cationic porphyrin TMPyP4 destabilizes the complex.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::4db15efe290214a0330733068f912c76 https://pubmed.ncbi.nlm.nih.gov/28296179 Zobrazit plný text záznamu Plný text