Autor: |
James A, Goetz, Noah M, Kuehfuss, Alexander J, Botschner, Shawna, Zhu, Laura K, Thompson, Georgina, Cox |
Rok vydání: |
2022 |
Předmět: |
|
Zdroj: |
Microbiology (Reading, England). 168(11) |
ISSN: |
1465-2080 |
Popis: |
Bacterial efflux pumps exhibit functional interplay that can translate to additive or multiplicative effects on resistance to antimicrobial compounds. In diderm bacteria, two different efflux pump structural types - single-component inner membrane efflux pumps and cell envelope-spanning multicomponent systems - cooperatively export antimicrobials with cytoplasmic targets from the cell. Harnessing our recently developed efflux platform, which is built upon an extensively efflux-deficient strain of |
Databáze: |
OpenAIRE |
Externí odkaz: |
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