| Autor: |
L, Briedigkeit, M, Ulmer, U, Göbel, R, Natusch, E, Reinhold-Keller, W L, Gross |
| Rok vydání: |
1993 |
| Předmět: |
|
| Zdroj: |
Advances in experimental medicine and biology. 336 |
| ISSN: |
0065-2598 |
| Popis: |
Treatment and outcome of 111 patients who fell ill with Wegener's granulomatosis (WG) between 1966 and 1990 were analysed retrospectively. Two regimens of treatment were distinguished: "conventional" treatment, i.e. daily application of cyclophosphamide/corticosteroids (FAUCI scheme) or azathioprine/corticosteroids or corticosteroids alone, and "stage-adapted" treatment, characterized by change of different treatments (e.g. cyclophosphamide pulse therapy, cotrimoxazole) according to the extent and activity of disease. In patients who received stage-adapted treatment, exacerbations occurred significantly more frequent than in conventionally treated patients, while lethal outcome was much more frequent in conventionally treated patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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