| Autor: |
Mei-Rong, Zang, Lan-Ting, Liu, Shu-Hui, Deng, Lu-Gui, Qiu |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Zhongguo shi yan xue ye xue za zhi. 29(5) |
| ISSN: |
1009-2137 |
| Popis: |
To investigate the expression of cell division cycle protein 37 (Cdc37) in multiple myeloma (MM) and its effect on MM cell proliferation.The expression of Cdc37 mRNA in CD138Cdc37 was highly expressed in newly diagnosed CD138Cdc37 is highly expressed in newly diagnosed MM patients. Inhibition of Cdc37 results in decreased proliferation activity and GCdc37在多发性骨髓瘤中的表达及其参与骨髓瘤细胞增殖的研究.探讨细胞分裂周期蛋白37（Cdc37）在多发性骨髓瘤（MM）中的表达及其对MM细胞增殖的影响。.采用实时定量PCR技术检测63例初治MM患者及8例正常人CD138与正常人相比，Cdc37在初治MM患者CD138Cdc37在初治MM患者中高表达，下调Cdc37可抑制MM细胞NCI-H929的增殖活性，诱导细胞周期阻滞于G |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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