p38 mitogen activated protein kinase mediates cardiac Na
| Autor: | Romina G, Díaz, Daiana S, Escudero, María S, Brea, Patricio E, Morgan, Néstor G, Pérez |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase 3 Sodium-Hydrogen Exchanger 1 Sodium-Hydrogen Exchangers MAP Kinase Signaling System Myocardium Heart p38 Mitogen-Activated Protein Kinases Sildenafil Citrate Rats Enzyme Activation Animals Protein Phosphatase 2 Phosphorylation Rats Wistar Acidosis Proto-Oncogene Proteins c-akt |
| Zdroj: | European journal of pharmacology. 849 |
| ISSN: | 1879-0712 |
| Popis: | Since the original description as potent antianginal compounds, phosphodiesterase 5A inhibitors have continuously increased their possible therapeutic applications. In the heart, Sildenafil was shown to protect against an ischemic insult by decreasing cardiac Na |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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