| Autor: |
Iu S, Mardynskiĭ, V F, Lopatin, V A, Bizer |
| Rok vydání: |
2007 |
| Předmět: |
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| Zdroj: |
Voprosy onkologii. 53(5) |
| ISSN: |
0507-3758 |
| Popis: |
An evaluation of the end results of combined treatment for osteogenic sarcoma by standard chemoradiotherapy (n = 66) and novel thermochemical therapy (n = 108) using local ultrasound hyperthermia (total number--174) demonstrated their dependence on the temperature range in target tumor tissues. Use of subhypertemperatures of 39--41-45 deg.C (TTD--36 Gy) did not improve the results of treatment. However, 41-45 deg.C (TTD--36 Gy) was followed by a significant increase in 3- and 5-year survival and improved quality of life in cured patients as compared with those receiving standard radiotherapy (TTD--60-110 Gy). Hyperthermic therapeutic effect in osteogenic sarcoma depends on certain conditions. Effective temperatures can generally be reached in patients with relatively large-size tumors and rather thin coats of subcutaneous fat. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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