Relationship between autoimmune thyroid disease and nephropathy
| Autor: | Zhao, Liping, Liu, Yunxiao, Su, Hongchang, Shi, Xiangzhen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
endocrine system Glomerulosclerosis Focal Segmental Thyroiditis Autoimmune Observational Study Receptors Thyrotropin Hashimoto Disease Middle Aged Thyroid Function Tests antithyroglobulin antibody Kidney Glomerulonephritis Membranous Immunohistochemistry Iodide Peroxidase Thyroglobulin nephropathy Humans Female antithyroid peroxidase antibody autoimmune thyroid disease Correlation of Data Research Article Autoantibodies |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 0025-7974 |
| Popis: | The association of nephropathy with autoimmune thyroid disease (AITD) has been reported previously. However, there is limited information on the relationship between thyroid autoantibodies and nephropathy. A retrospective study was conducted using the medical records of 246 patients with nephropathy, 82 of whom had concurrent AITD. General characteristics, thyroid function, autoantibodies, and the pathological types of nephropathy were analyzed. Immunohistochemistry was used to detect the thyroglobulin antibody (TG-Ab) and thyroid peroxidase antibody (TPO-Ab) in the kidneys. We found nephropathy patients with AITD exhibited higher serum levels of TPO-Ab, TG-Ab, thyroid-stimulating hormone receptor antibody (TR-Ab), and immunoglobulin G (IgG) (P |
| Databáze: | OpenAIRE |
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