| Autor: |
P D, Pucci, D, Antoniucci, V, Boddi, L, Bolognese, P, Buonamici, G, Cerisano, G, Moschi, A, Santini, M, Trapani, P F, Fazzini |
| Rok vydání: |
1998 |
| Předmět: |
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| Zdroj: |
Giornale italiano di cardiologia. 28(5) |
| ISSN: |
0046-5968 |
| Popis: |
This study was designed to prospectively assess the ability of the 12-lead electrocardiogram (ECG) and optimal ECG criteria to predict late functional recovery in patients with acute myocardial infarction (AMI) treated with primary coronary angioplasty (PTCA) BACKGROUND: A simple clinical method to predict clinical outcome in patients with reperfused AMI is highly desirable from a clinical point of view.Seventy-five patients with AMI treated with successful PTCA (TIMI flow grade 3 and residual stenosis30%) underwent serial 12-lead ECG before PTCA and every hour for the first 6 hours and then at 9, 12, and 18 hours after PTCA. All patients underwent two-dimensional echocardiography before PTCA and 1 and 6 months later for the evaluation of regional wall motion. The ST segment level in the lead exhibiting the maximal ST elevation (ST increase max) and the sum of the ST segment elevation (sigma ST increases) were calculated on initial ECG and a cut-off values ofor = 50% reduction of ST increases max sigma ST increases elevation and sampling intervals were correlated with late functional recovery. A wall motion score index (WMSI: 1 = normal to 4 = dyskinesia) and 16-segment model were used. Reversible dysfunction was defined as a decrease ofor = 0.22 in WMSI.At univariate analysis aor = 50% reduction of both ST increases max and sigma ST increases was related to late functional recovery. Multiple logistic regression analysis revealed that reduction of sigma ST increases was the most powerful predictor of late functional recovery (p = 0.008). Aor = 50% reduction of sigma ST increase within 4 hours of PTCA provided the optimal criterion for predicting late functional recovery.Rapid reduction of sigma ST increases elevation is an accurate predictor of left ventricular functional recovery in patients with AMI treated with primary PTCA. Optimal criteria include a reduction in sigma ST increases elevationor = 50% within 4 hours of PTCA. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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