Popis: |
Fibronectin, a high-molecular glycoprotein, one of acute-phase proteins, contributes to cellular proliferation and macrophagal activity regulation, and its blood plasma levels are an indicator of the reticuloendothelial system functional activity. Blood plasma fibronectin levels were measured in psoriasis patients before and after hemoperfusion. These levels were found significantly increased in the course of hemoperfusion treatment, this being associated with disappearance of psoriatic elements. A correlation between blood plasma fibronectin level and NBT test parameters, on the one hand, and severity of psoriasis course and efficacy of therapy, on the other, has been revealed. |