Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge
| Autor: | Andrew J, MacGinnitie, Loren D, Walensky, Stuart E, Turvey, Jordan S, Orange, Francisco A, Bonilla, Lewis B, Silverman, Hans, Oettgen |
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| Rok vydání: | 2003 |
| Předmět: |
Male
Antimetabolites Antineoplastic Adolescent Dose-Response Relationship Drug Urticaria Pruritus Antipruritics Precursor Cell Lymphoblastic Leukemia-Lymphoma Ranitidine Diphenhydramine Methotrexate Histamine H2 Antagonists Anti-Allergic Agents Humans Drug Therapy Combination Drug Eruptions Anaphylaxis Skin Tests |
| Zdroj: | Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. 14(5) |
| ISSN: | 0905-6157 |
| Popis: | We report the management of a 15-year-old boy with an anaphylactic or anaphylactoid response to his first dose of methotrexate during induction therapy for acute lymphoblastic leukemia (ALL). Because weekly methotrexate therapy is an important component of continuation chemotherapy for pediatric ALL, a stepwise graded challenge was employed to achieve drug tolerance. |
| Databáze: | OpenAIRE |
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