24-hour study of thawed erythrocytes. Value of a protective solution

Autor: V, Camberlein, S, Goll, D, Ehrard, O, Kane
Jazyk: francouzština
Rok vydání: 1987
Předmět:
Zdroj: Revue francaise de transfusion et immuno-hematologie. 30(3)
ISSN: 0338-4535
Popis: We have previously shown that thawed RBC concentrate can be stored at +4 degrees C during 9 days if resuspended in a synthetic medium: ESOC. We now report the in vitro evolution of thawed RBC stored with or without protective medium during the 24 hours legal time-limit. (Formula: see text) We show that without protection, the ATP and 2,3-DPG levels remain acceptable, but spontaneous or caused hemolysis is high. The level of free Hb is soon over the legal limit. The addition of our protective medium enhances ATP and hemolysis is strongly reduced. We conclude that a protective medium should be added to all thawed RBC concentrates.
Databáze: OpenAIRE