[Relationship between interferon priming effect and functional activity of human blood cells]

Autor: S B, Cheknev, A M, Amchenkova, A N, Narovlianskiĭ
Rok vydání: 2002
Předmět:
Zdroj: Voprosy virusologii. 47(2)
ISSN: 0507-4088
Popis: Relationship between the priming effects of interferon (IFN)-alpha and -gamma and the standard IFN production by peripheral blood leukocytes was evaluated in 25 volunteers (13 men and 12 women, mean age 35.3 years). Priming of IFN-alpha and IFN-gamma production positively correlated with the standard IFN-alpha and IFN-gamma synthesis, respectively. On the other hand, primed production of IFN-alpha negatively correlated with that of IFN-gamma. Possible role of types I and II IFN interactions in the maintenance of physiological regulatory balance is discussed.
Databáze: OpenAIRE