Synthesis and pharmacological properties of nebivolol, a new antihypertensive compound

Autor:	G, Van Lommen, M, De Bruyn, M, Schroven
Rok vydání:	1990
Předmět:	Isomerism Ethanolamines Adrenergic beta-Antagonists Guinea Pigs Animals Benzopyrans Rabbits In Vitro Techniques Nebivolol Rats
Zdroj:	Journal de pharmacie de Belgique. 45(6)
ISSN:	0047-2166
Popis:	The synthesis of alpha,alpha' (iminobis(methylene]-bis-(3,4-dihydro-2H-1benzopyran-2-metha nol) derivatives and the stereochemistry and pharmacological profile of this new class of antihypertensive compounds are described. Finally, the selection and pharmacological profile of the preferred compound of this series, nebivolol and its enantiomers, is discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::3d3497a918bbd0f252e0d868498c8c93 https://pubmed.ncbi.nlm.nih.gov/1982295 Zobrazit plný text záznamu