[Actinomyces streptomycini mutants blocked in the biosynthesis of the streptobiosamine portion of the streptomycin molecule]

Autor: O L, Krasil'nikov, L N, Anisova, A S, Khokhlov
Rok vydání: 1978
Předmět:
Zdroj: Antibiotiki. 23(2)
ISSN: 0003-5637
Popis: Four low active mutants of Act. streptomycini were obtained under the effect of nitrozo-methylbiuret. The mutants increased their antibiotic production level, when streptobiosamine was present in the formentation medium. It was shown that in 3 out of the 4 mutants the highest antibiotic yield was in the medium containing streptobiosamine in an amount of 1 mg/ml and in 1 strain the highest yield was in the medium with 0.5 mg/ml of streptobiosamine. When the mutants were grown in a medium containing N-methyl-L-glucosamine no increase in streptomycin production was registered.
Databáze: OpenAIRE