Autor: |
Kokame, Gregg T., Yannuzzi, Nicolas A., Shantha, Jessica G., Yamane, Maya, Relhan, Nidhi, Gross, Jeffrey, Ryan, Edwin H., Flynn, Harry W. |
Jazyk: |
angličtina |
Rok vydání: |
2021 |
Předmět: |
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Zdroj: |
Retin Cases Brief Rep |
Popis: |
PURPOSE: To report patients who demonstrated an alteration in the clinical and optical coherence tomography (OCT) features of neovascular age-related macular degeneration (AMD) following resolution of endophthalmitis. METHODS: Retrospective case series of the subsequent changes in the macula and need for anti-VEGF therapy in patients with neovascular AMD who developed endophthalmitis following intravitreal injection. RESULTS: The study included 7 eyes of 7 patients with follow-up ranging between 3 months and 11 years. The vitreous cultures (n=7) prior to intravitreal antibiotic injection were the following: culture negative (4) and coagulase-negative Staphylococcus (3). Initial treatment included vitreous tap and injection (4) and pars plana vitrectomy (PPV, 3). In 5/7 eyes, the OCT showed resolution of subretinal fluid and serous pigment epithelial detachment and there was no additional anti-VEGF treatment administered. CONCLUSION: After successful treatment of endophthalmitis in patients with neovascular AMD, there was relative involution of the maculopathy and reduced anti-VEGF treatment burden in this series. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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