| Autor: |
B Ia, Drozdovskiĭ, R A, Roziev, A Ia, Goncharova |
| Rok vydání: |
1991 |
| Předmět: |
|
| Zdroj: |
Meditsinskaia radiologiia. 36(7) |
| ISSN: |
0025-8334 |
| Popis: |
A study was made of the behaviour of human serum albumin microspheres--SAM-- (USSR) during intraarterial selective infusion of them in the hepatic artery of rabbits. 125I was used as a radioactive tracing agent. Accumulation of the agent in organs and its excretion were investigated over time by radiometry in vivo and in vitro. Distribution of 125I-SAM in the liver at administration of different amounts of the radioactive drug was also investigated. A mathematical formula of calculation of the optimum amount of administered microspheres was proposed. A conclusion was made of a possibility of the use of the SAM as a carrier of short-lived radionuclides for endovascular radiotherapy of malignant hepatic tumors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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