Mucosal dysplasia. A major predictor of cancer following ileorectal anastomosis

Autor:	W R, Johnson, F T, McDermott, E, Pihl, E S, Hughes
Rok vydání:	1983
Předmět:	Adult Time Factors Rectal Neoplasms Biopsy Rectum Humans Colitis Ulcerative Intestinal Mucosa Precancerous Conditions Colectomy Follow-Up Studies Probability
Zdroj:	Diseases of the colon and rectum. 26(11)
ISSN:	0012-3706
Popis:	Fifty patients with ulcerative colitis managed by colectomy and ileorectal anastomosis had rectal biopsies performed in the period 1967 to 1972. Follow-up information was available on all patients. Thirty-nine patients were reviewed and rectal biopsies performed in the 1980 to 1982 period. Three patients had developed rectal cancer in the period 1975 to 1980, and two rectal cancers were detected in the 1980 to 1982 follow-up period. All cancers occurred in patients with a diagnosis of moderate or severe dysplasia in biopsy specimens from the 1969 to 1972 period. The probability of developing rectal cancer after a diagnosis of moderate or severe dysplasia in this series reached 42 per cent at nine years from diagnosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::38dfdf666a0e9f0fc2687e0fbf6de644 https://pubmed.ncbi.nlm.nih.gov/6628140 Zobrazit plný text záznamu Full text from SpringerLink