IgM and IgG anti-F(ab')2 antibodies in rheumatoid arthritis and systemic lupus erythematosus

Autor:	R, Heimer, L D, Wolfe, J L, Abruzzo
Rok vydání:	1982
Předmět:	Arthritis Rheumatoid Immunoglobulin Fab Fragments Immunoglobulin M Rheumatoid Factor Immunoglobulin G Radioimmunoassay Humans Lupus Erythematosus Systemic Antibodies Anti-Idiotypic
Zdroj:	Arthritis and rheumatism. 25(11)
ISSN:	0004-3591
Popis:	Radioimmunoassays for anti-F(ab')2 antibodies, which feature the use of goat anti-human Fc antibody for correcting potentiation of IgM anti-F(ab')2 antibody titers by endogenous IgM anti-Fc antibodies (rheumatoid factors), are described. Individuals with classic rheumatoid arthritis had significantly more IgM anti-F(ab')2 antibody (P less than 0.001) and IgG anti-F(ab')2 antibody (P = 0.05) than did individuals with systemic lupus erythematosus or normal volunteers. There is some similarity in patterns of isotype distribution of anti-F(ab')2 antibodies and rheumatoid factors.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::38b017c375599a126b5957e97c6de185 https://pubmed.ncbi.nlm.nih.gov/6982718 Zobrazit plný text záznamu Plný text