Autor: |
E D, Sverdlov, N F, Kalinina |
Rok vydání: |
1983 |
Předmět: |
|
Zdroj: |
Bioorganicheskaia khimiia. 9(4) |
ISSN: |
0132-3423 |
Popis: |
Incomplete modification of DNA fragments labeled at one terminus with N-bromosuccinimide is shown to be useful for localization of G and C residues along the polynucleotide chain. After N-bromosuccinimide treatment the fragments can be split at modified residues with piperidine. The rate of the reaction of the single-stranded fragments is extremely fast and much higher than that of double-stranded DNA. The modification can be used for structure and function studies on DNA. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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