Genetic polymorphism in

Autor: Sabine, Visser, Stijn, Koolen, Nadine, van Donk, Nico, van Walree, Cor, van der Leest, Robin, Cornelissen, Ron, van Schaik, Ron, Mathijssen, Joachim, Aerts, Bruno H, Stricker
Rok vydání: 2020
Předmět:
Zdroj: Thorax. 76(11)
ISSN: 1468-3296
Popis: Patients with advanced non-small-cell lung cancer who are treated with pemetrexed display a wide variation in clinical response and toxicity. In this prospective, multicentre cohort study, we investigated the association with treatment effectiveness and toxicity of 10 polymorphisms in nine candidate genes, covering the folate pathway (
Databáze: OpenAIRE