The effect of geometry on tumor thermal profile and its use in tumor functional state estimation

Autor: Michal, Tepper, Asaf, Shoval, Israel, Gannot
Rok vydání: 2014
Předmět:
Zdroj: Journal of biophotonics. 8(3)
ISSN: 1864-0648
Popis: Thermal differences between transplanted tumors and tumors in humans prevent the implementation of thermographic methods developed in mice models to human models and vise-versa. Transplantable tumors tend to have an extruding shape, which may affect the thermal patterns. This hypothesis was studied in phantom experiments and simulations. A correlation between tumor dimensions and relative temperature was found and used to estimate tumor functional state from previously published in vivo experiments. A correlation was found between temperature differences and tumor growth rates (tumor aggressiveness) and the effect of tumor treatment was demonstrated, showing the potential for in vivo, non-invasive tumor monitoring.
Databáze: OpenAIRE