[Thrombotic thrombocytopenic purpura: do not ignore cardiac involvement]

Autor:	M, Puyade, J, Badin, B, Quéron, L, Christiaens, N, Varroud-Vial, F, Pierre, O, Pourrat
Jazyk:	francouzština
Rok vydání:	2012
Předmět:	Adult HELLP Syndrome Heart Diseases Purpura Thrombotic Thrombocytopenic Pregnancy Pregnancy Complications Cardiovascular Pregnancy Complications Hematologic Humans Female Magnetic Resonance Imaging
Zdroj:	La Revue de medecine interne. 35(4)
ISSN:	1768-3122
Popis:	Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy due to ADAMTS13 deficiency (a von Willebrand factor's metalloprotease) with multiple organs' involvement, one of which may be the heart.We report a 29-year-old woman who presented a TTP during her last trimester of pregnancy, under the features of a HELLP syndrome. After caesarean section, cardiac involvement was revealed by chest pain, ECG changes, antero-septal hypokinesia and troponin rise. Cardiac MRI found no large-vessel ischemic heart disease and confirmed hypokinesia.When TTP is diagnosed, cardiac involvement must be systematically investigated by ECG and troponin assay because of the risk of a cardiac arrest.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::367c5259228739ef5955973eb6c5afbc https://pubmed.ncbi.nlm.nih.gov/23711951 Zobrazit plný text záznamu Full Text from ScienceDirect