| Autor: |
T, Jeanfaivre, A, Chassevent, J, Berruchon, L, Savary, M F, Chrétien, J, Geslin, F, Larra, E, Tuchais |
| Jazyk: |
francouzština |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Bulletin du cancer. 82(5) |
| ISSN: |
0007-4551 |
| Popis: |
The authors determined the desoxyribonucleic acid (DNA) content of 45 small-cell lung cancers, by flow-cytometry (FC), from bronchial brushings to asses the prognostic meaning of the DNA index, the percentage of cells in DNA synthesis phase (% S) and the ploidy. Moreover, the value of this tumorous cells brushing was assessed for Flow-cytometric analysis. Bronchial brushing offers some advantages opposite to biopsies, but the low quantity of collected cells reduces the number of tumors analysable by FC. The output is low (39%) for determination of DNA index, and moreover low (22%) for determination of % S. In regard to the flow-cytometry analysis, the DNA content does not show any significant difference of survival where as the % S is related to survival, but it seems to be paradoxical in this study. Indeed, patients with small-cell lung cancer associated to high cells' percentage in DNA synthesis phase have the longest survival. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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