[Antibody formation to morphine and neuromediators in morphinized rats]

Autor: S I, Tronnikov, N B, Gamaleia, A G, Veretinskaia, E V, Borisova, S K, Sudakov, I P, Anokhina
Rok vydání: 1992
Předmět:
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny. 114(12)
ISSN: 0365-9615
Popis: The paper demonstrates induction of antibodies to morphine and neurotransmitters (dopamine, norepinephrine, serotonin) in rats treated with intraperitoneal injections of morphine hydrochloride during 2 and 4 weeks in increasing doses. A contribution of such antibodies to the mechanisms of morphine tolerance and formation of physical dependence is considered.
Databáze: OpenAIRE