Autor: |
Stefanie, Liening, Jana, Fischer, Hans, Jagusch, Georg, Pohnert, Oliver, Höcker, Christian, Neusüß, Oliver, Werz, Gerhard K E, Scriba, Ulrike, Garscha |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Prostaglandinsother lipid mediators. 152 |
ISSN: |
1098-8823 |
Popis: |
Biologically active glutathione (GSH) conjugates of oxygenated fatty acids comprise a group of pro- and anti-inflammatory lipid mediators. While arachidonic acid (AA)-derived conjugates, as the cysteinyl leukotrienes (cys-LTs) and eoxins (EXs) have pro-inflammatory properties, conjugates in tissue regeneration (CTRs) biosynthesized from docosahexaenoic acid (DHA) exhibit pro-resolving activity. Human platelets express abundant amounts of platelet-type 12-lipoxygenase (pt12-LOX) and leukotriene C |
Databáze: |
OpenAIRE |
Externí odkaz: |
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