Autor: |
Ikuko, Matsumura, Kunio, Yanagisawa, Yoshiyuki, Ogawa, Hiroaki, Shimizu, Takuma, Ishizaki, Takeki, Mitsui, Hideki, Uchiumi, Yuri, Uchiyama, Naomichi, Matsumuto, Hiroshi, Handa |
Rok vydání: |
2018 |
Předmět: |
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Zdroj: |
[Rinsho ketsueki] The Japanese journal of clinical hematology. 59(3) |
ISSN: |
0485-1439 |
Popis: |
Hemophilic pseudotumors can occur in patients with hemophilia because of recurrent bleeding and poor hemostasis. A man in his 30s with hemophilia B and human immunodeficiency virus/hepatitis C virus co-infection complicated by liver cirrhosis presented with a large pseudotumor in the left iliopsoas muscle. However, resting to stop bleeding was difficult with his daily work. Osteolytic changes in the left ilium progressed over 8 years. A large osteolytic pseudotumor in the pelvis was also incidentally identified in his younger brother during his 30s. The same mutations in F9 (p. Arg294Gln, hemizygous mutation) associated with a non-severe phenotype were detected in both brothers. The clinical courses of the brothers suggested that large pseudotumors can occur in patients with non-severe hemophilia and underline the importance of patient education. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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