Clinical experience with endothelin receptor antagonists in chronic heart failure

Autor:	A, Seed, M P, Love, J J, McMurray
Rok vydání:	2001
Předmět:	Endothelin Receptor Antagonists Heart Failure Clinical Trials as Topic Endothelin-1 Receptors Endothelin Chronic Disease Hemodynamics Humans Middle Aged
Zdroj:	Heart failure reviews. 6(4)
ISSN:	1382-4147
Popis:	Both ET(A) selective and dual, ET(A/B), receptor antagonists have favourable short- and longer-term haemodynamic actions in patients with acute and chronic heart failure. Their effect on neurohumoral measures is not yet fully determined. Two moderately large, medium-duration studies have examined the effect of dual ET(A/B) receptor antagonists on clinical status, reaching conflicting conclusions. One large scale, long-term, morbidity mortality evaluation is underway with bosentan.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::2975b9fc26fffa921b9cd8ae0ae17103 https://pubmed.ncbi.nlm.nih.gov/11447306 Zobrazit plný text záznamu Full text from SpringerLink