Linking in vitro estrogenicity to adverse effects in the inland silverside (Menidia beryllina)

Autor: Alvine C, Mehinto, Kevin J, Kroll, B Sumith, Jayasinghe, Candice M, Lavelle, Darcy, VanDervort, Olanike K, Adeyemo, Steven M, Bay, Keith A, Maruya, Nancy D, Denslow
Rok vydání: 2017
Předmět:
Zdroj: Environmental toxicology and chemistry. 37(3)
ISSN: 1552-8618
Popis: High-throughput cell assays that detect and integrate the response of multiple chemicals acting via a common mode of action have the potential to enhance current environmental monitoring practices. Establishing the linkage between in vitro and in vivo responses is key to demonstrating that in vitro cell assays can be predictive of ecologically relevant outcomes. The present study investigated the potency of 17β-estradiol (E2), estrone (E1), nonylphenol (NP), and treated wastewater effluent using the readily available GeneBLAzer
Databáze: OpenAIRE